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It was discovered that naltrexone and bupropion combined, that could be marketed in the future as Contrave, give better weight loss results than diet and exercise alone.

Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err to the side of caution and permit the FDA do its job and demand some study be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies are in business to generate money and that they would say everything to keep people on his or her medications.

Researchers found out that participants taking this drug for a year, dropped excess weight within a month and have kept the load off through the 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer.

Combo-pilling will be the newest fad or better yet the newest in the future under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular will be the fact that since right now there aren't long term prescription weightloss pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be licensed by the FDA.

Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug also can raise blood pressure level and heartbeat, and mustn't be used in people with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.

The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high blood pressure, as well as by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking.


Acamprosate also activly works to eliminate the need to drink through the elimination of the the cravings for alcohol consumption. The major difference between Naltrexone and Acamprosate is the fact that Acamprosate isn't yet accessible in the United States. While it may be widely studied in Europe the complete chemical reason that it works remains to be unknown. It is thought that it disrupts receptors inside brain which process glutamate, which in essence alters the best way ones body reacts to alcohol intake. Several of the European studies show a lot of promise with Acamprosate for the reason that some of the patients had an almost double success rate for staying sober.